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Gli3 silencing enhances cyclopamine suppressive effects on ovarian cancer

Ovarian cancer is a leading gynecological malignancy associated with high mortality. Hedgehog signaling has been found to be important for cell proliferation and tumor growth for multiple cancers, including ovarian cancer. The present study showed that the drug cyclopamine, which blocks the hedgehog...

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Detalles Bibliográficos
Autores principales: Liu, Hai-Yan, Dong, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218910/
https://www.ncbi.nlm.nih.gov/pubmed/25378935
http://dx.doi.org/10.2147/OTT.S57346