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Factors associated with adherence to medication among depressed patients from Saudi Arabia: a cross-sectional study

BACKGROUND: Several studies have investigated the factors associated with adherence to antidepressants, with inconsistent conclusions. However, no similar study has investigated this issue among patients diagnosed with major depressive disorder in Saudi Arabia. The aim of this study is to explore pa...

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Autores principales: Al Jumah, Khalaf, Hassali, Mohamed Azmi, Al Qhatani, Dalal, El Tahir, Kamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218914/
https://www.ncbi.nlm.nih.gov/pubmed/25378929
http://dx.doi.org/10.2147/NDT.S71697
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author Al Jumah, Khalaf
Hassali, Mohamed Azmi
Al Qhatani, Dalal
El Tahir, Kamal
author_facet Al Jumah, Khalaf
Hassali, Mohamed Azmi
Al Qhatani, Dalal
El Tahir, Kamal
author_sort Al Jumah, Khalaf
collection PubMed
description BACKGROUND: Several studies have investigated the factors associated with adherence to antidepressants, with inconsistent conclusions. However, no similar study has investigated this issue among patients diagnosed with major depressive disorder in Saudi Arabia. The aim of this study is to explore patients’ adherence to antidepressant medications, and the factors associated with adherence. METHODS: A non-experimental cross-sectional design was used to measure adherence to antidepressants among major depressive disorder patients, and the factors associated with adherence. The patients were recruited from the outpatient clinic at the Al-Amal Complex for Mental Health in Riyadh, Saudi Arabia, between August 2013 and January 2014. Eligible participants met with one of the research coordinators for assessment of their adherence. Adherence was investigated indirectly by use of the Morisky Medication Adherence Scale, and patients’ beliefs were assessed through the Beliefs about Medicine Questionnaire. Information about the severity of their depression, demographics, and other study variables were collected. RESULTS: A total of 403 patients met the inclusion criteria and participated in the study. Of those, 203 (50.37%) were females, while the remaining 200 (49.6%) were males. There was an average age of 39 years (standard deviation, ±11 years). Half of the patients (52.9%) reported low adherence to their antidepressant medication, with statistically significant differences between the low adherence and high adherence scores relating to sex, age, and duration of illness. CONCLUSION: Low medication adherence is a common problem among major depressive disorder patients in Saudi Arabia. Medication-taking behavior among depressed patients is influenced by several factors, mainly patients’ beliefs regarding antidepressants. This study has improved the understanding of the factors associated with adherence to antidepressants.
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spelling pubmed-42189142014-11-06 Factors associated with adherence to medication among depressed patients from Saudi Arabia: a cross-sectional study Al Jumah, Khalaf Hassali, Mohamed Azmi Al Qhatani, Dalal El Tahir, Kamal Neuropsychiatr Dis Treat Original Research BACKGROUND: Several studies have investigated the factors associated with adherence to antidepressants, with inconsistent conclusions. However, no similar study has investigated this issue among patients diagnosed with major depressive disorder in Saudi Arabia. The aim of this study is to explore patients’ adherence to antidepressant medications, and the factors associated with adherence. METHODS: A non-experimental cross-sectional design was used to measure adherence to antidepressants among major depressive disorder patients, and the factors associated with adherence. The patients were recruited from the outpatient clinic at the Al-Amal Complex for Mental Health in Riyadh, Saudi Arabia, between August 2013 and January 2014. Eligible participants met with one of the research coordinators for assessment of their adherence. Adherence was investigated indirectly by use of the Morisky Medication Adherence Scale, and patients’ beliefs were assessed through the Beliefs about Medicine Questionnaire. Information about the severity of their depression, demographics, and other study variables were collected. RESULTS: A total of 403 patients met the inclusion criteria and participated in the study. Of those, 203 (50.37%) were females, while the remaining 200 (49.6%) were males. There was an average age of 39 years (standard deviation, ±11 years). Half of the patients (52.9%) reported low adherence to their antidepressant medication, with statistically significant differences between the low adherence and high adherence scores relating to sex, age, and duration of illness. CONCLUSION: Low medication adherence is a common problem among major depressive disorder patients in Saudi Arabia. Medication-taking behavior among depressed patients is influenced by several factors, mainly patients’ beliefs regarding antidepressants. This study has improved the understanding of the factors associated with adherence to antidepressants. Dove Medical Press 2014-10-28 /pmc/articles/PMC4218914/ /pubmed/25378929 http://dx.doi.org/10.2147/NDT.S71697 Text en © 2014 Al Jumah et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Al Jumah, Khalaf
Hassali, Mohamed Azmi
Al Qhatani, Dalal
El Tahir, Kamal
Factors associated with adherence to medication among depressed patients from Saudi Arabia: a cross-sectional study
title Factors associated with adherence to medication among depressed patients from Saudi Arabia: a cross-sectional study
title_full Factors associated with adherence to medication among depressed patients from Saudi Arabia: a cross-sectional study
title_fullStr Factors associated with adherence to medication among depressed patients from Saudi Arabia: a cross-sectional study
title_full_unstemmed Factors associated with adherence to medication among depressed patients from Saudi Arabia: a cross-sectional study
title_short Factors associated with adherence to medication among depressed patients from Saudi Arabia: a cross-sectional study
title_sort factors associated with adherence to medication among depressed patients from saudi arabia: a cross-sectional study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218914/
https://www.ncbi.nlm.nih.gov/pubmed/25378929
http://dx.doi.org/10.2147/NDT.S71697
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