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Regulation of the effects of CYP2E1-induced oxidative stress by JNK signaling

The generation of excessive amounts of reactive oxygen species (ROS) leads to cellular oxidative stress that underlies a variety of forms of hepatocyte injury and death including that from alcohol. Although ROS can induce cell damage through direct effects on cellular macromolecules, the injurious e...

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Detalles Bibliográficos
Autores principales: Schattenberg, Jörn M., Czaja, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218941/
https://www.ncbi.nlm.nih.gov/pubmed/25462060
http://dx.doi.org/10.1016/j.redox.2014.09.004