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Regulation of the effects of CYP2E1-induced oxidative stress by JNK signaling
The generation of excessive amounts of reactive oxygen species (ROS) leads to cellular oxidative stress that underlies a variety of forms of hepatocyte injury and death including that from alcohol. Although ROS can induce cell damage through direct effects on cellular macromolecules, the injurious e...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218941/ https://www.ncbi.nlm.nih.gov/pubmed/25462060 http://dx.doi.org/10.1016/j.redox.2014.09.004 |