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Gefitinib loaded folate decorated bovine serum albumin conjugated carboxymethyl-beta-cyclodextrin nanoparticles enhance drug delivery and attenuate autophagy in folate receptor-positive cancer cells

BACKGROUND: Active targeting endocytosis mediated by the specific interaction between folic acid and its receptor has been a hotspot in biological therapy of many human cancers. Various studies have demonstrated that folate and its conjugates could facilitate the chemotherapeutic drug delivery into...

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Detalles Bibliográficos
Autores principales: Shi, Yijie, Su, Chang, Cui, Wenyu, Li, Hongdan, Liu, Liwei, Feng, Bo, Liu, Ming, Su, Rongjian, Zhao, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219096/
https://www.ncbi.nlm.nih.gov/pubmed/25358257
http://dx.doi.org/10.1186/s12951-014-0043-7