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Innate immunity but not NLRP3 inflammasome activation correlates with severity of stable COPD

BACKGROUND: In models of COPD, environmental stressors induce innate immune responses, inflammasome activation and inflammation. However, the interaction between these responses and their role in driving pulmonary inflammation in stable COPD is unknown. OBJECTIVES: To investigate the activation of i...

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Detalles Bibliográficos
Autores principales:	Di Stefano, Antonino, Caramori, Gaetano, Barczyk, Adam, Vicari, Chiara, Brun, Paola, Zanini, Andrea, Cappello, Francesco, Garofano, Elvira, Padovani, Anna, Contoli, Marco, Casolari, Paolo, Durham, Andrew L, Chung, Kian Fan, Barnes, Peter J, Papi, Alberto, Adcock, Ian, Balbi, Bruno
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2014
Materias:	Chronic Obstructive Pulmonary Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219154/ https://www.ncbi.nlm.nih.gov/pubmed/24430176 http://dx.doi.org/10.1136/thoraxjnl-2012-203062

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