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Partial inhibition and bilevel optimization in flux balance analysis
MOTIVATION: Within Flux Balance Analysis, the investigation of complex subtasks, such as finding the optimal perturbation of the network or finding an optimal combination of drugs, often requires to set up a bilevel optimization problem. In order to keep the linearity and convexity of these nested o...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219332/ https://www.ncbi.nlm.nih.gov/pubmed/24286232 http://dx.doi.org/10.1186/1471-2105-14-344 |