Vascular calcification is coupled with phenotypic conversion of vascular smooth muscle cells through Klf5-mediated transactivation of the Runx2 promoter

Both Klf5 (Krüppel-like factor 5) and Runx2 are involved in phenotypic switching of VSMC (vascular smooth muscle cells). However, the potential link between Klf5 and Runx2 in mediating vascular calcification remains unclear. The aim of the present study was to elucidate the actual relationship betwe...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Zheng, Bin, Zhou, Pei-pei, Zhang, Ruo-Nan, He, Ming, Yang, Zhan, Wen, Jin-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2014
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219426/
https://www.ncbi.nlm.nih.gov/pubmed/25205373
http://dx.doi.org/10.1042/BSR20140103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219426/
https://www.ncbi.nlm.nih.gov/pubmed/25205373
http://dx.doi.org/10.1042/BSR20140103

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