Cargando…

Vascular calcification is coupled with phenotypic conversion of vascular smooth muscle cells through Klf5-mediated transactivation of the Runx2 promoter

Both Klf5 (Krüppel-like factor 5) and Runx2 are involved in phenotypic switching of VSMC (vascular smooth muscle cells). However, the potential link between Klf5 and Runx2 in mediating vascular calcification remains unclear. The aim of the present study was to elucidate the actual relationship betwe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Jing, Zheng, Bin, Zhou, Pei-pei, Zhang, Ruo-Nan, He, Ming, Yang, Zhan, Wen, Jin-Kun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2014
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219426/ https://www.ncbi.nlm.nih.gov/pubmed/25205373 http://dx.doi.org/10.1042/BSR20140103

Ejemplares similares

Phenotypic plasticity of vascular smooth muscle cells in vascular calcification: Role of mitochondria
por: Liu, Yan Zhong, et al.
Publicado: (2022)

Cdon suppresses vascular smooth muscle calcification via repression of the Wnt/Runx2 Axis
por: Ahn, Byeong-Yun, et al.
Publicado: (2023)

Kalkitoxin attenuates calcification of vascular smooth muscle cells via RUNX-2 signaling pathways
por: Shrestha, Saroj K, et al.
Publicado: (2023)

KLF4-PFKFB3-driven glycolysis is essential for phenotypic switching of vascular smooth muscle cells
por: Zhang, Xinhua, et al.
Publicado: (2022)

Characterization of Circular RNAs in Vascular Smooth Muscle Cells with Vascular Calcification
por: Ryu, Juhee, et al.
Publicado: (2019)

MiR-9 promotes the phenotypic switch of vascular smooth muscle cells by targeting KLF5
por: LU, Xiaochun, et al.
Publicado: (2019)

Roles of Vascular Smooth Muscle Cells in Atherosclerotic Calcification
por: Woo, Sang-Ho, et al.
Publicado: (2023)

Long noncoding RNAs in vascular smooth muscle cells regulate vascular calcification
por: Jeong, Geon, et al.
Publicado: (2019)

The Role of Sirtuins in Osteogenic Differentiation of Vascular Smooth Muscle Cells and Vascular Calcification
por: Wang, Shuangshuang, et al.
Publicado: (2022)

HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype
por: Malhotra, Rajeev, et al.
Publicado: (2019)

Vascular Smooth Muscle Cell Neutral Sphingomyelinase 2 in the Release of Exosomes and Vascular Calcification
por: Pavlic, Angelina, et al.
Publicado: (2022)

RNA sequencing to determine the contribution of kinase receptor transactivation to G protein coupled receptor signalling in vascular smooth muscle cells
por: Kamato, Danielle, et al.
Publicado: (2017)

Exosomes, the message transporters in vascular calcification
por: Zhang, Chao, et al.
Publicado: (2018)

Tanshinone II A attenuates vascular remodeling through klf4 mediated smooth muscle cell phenotypic switching
por: Lou, Guanhua, et al.
Publicado: (2020)

Porphyromonas gingivalis‐derived outer membrane vesicles promote calcification of vascular smooth muscle cells through ERK1/2‐RUNX2
por: Yang, Wen Wei, et al.
Publicado: (2016)

Regulatory mechanism of human vascular smooth muscle cell phenotypic transformation induced by NELIN
por: PEI, CHANGAN, et al.
Publicado: (2015)

Exosomes from hyperglycemia-stimulated vascular endothelial cells contain versican that regulate calcification/senescence in vascular smooth muscle cells
por: Li, Shuang, et al.
Publicado: (2019)

The Contribution of Extracellular Vesicles From Senescent Endothelial and Vascular Smooth Muscle Cells to Vascular Calcification
por: Mas-Bargues, Cristina, et al.
Publicado: (2022)

Poly(ADP-ribose) polymerase 1 accelerates vascular calcification by upregulating Runx2
por: Wang, Cheng, et al.
Publicado: (2019)

MicroRNA-223-3p inhibits vascular calcification and the osteogenic switch of vascular smooth muscle cells
por: Han, Yingchun, et al.
Publicado: (2021)

Critical Parameters of the In Vitro Method of Vascular Smooth Muscle Cell Calcification
por: Hortells, Luis, et al.
Publicado: (2015)

Differing calcification processes in cultured vascular smooth muscle cells and osteoblasts
por: Patel, Jessal J., et al.
Publicado: (2019)

Osteomodulin attenuates smooth muscle cell osteogenic transition in vascular calcification
por: Skenteris, Nikolaos T., et al.
Publicado: (2022)

ANGPTL4 stabilizes atherosclerotic plaques and modulates the phenotypic transition of vascular smooth muscle cells through KLF4 downregulation
por: Cho, Dong Im, et al.
Publicado: (2023)

How vascular smooth muscle cell phenotype switching contributes to vascular disease
por: Cao, Genmao, et al.
Publicado: (2022)

Low Levels of the Reverse Transactivator Fail to Induce Target Transgene Expression in Vascular Smooth Muscle Cells
por: Viceconte, Nikenza, et al.
Publicado: (2014)

GPCR transactivation signalling in vascular smooth muscle cells: role of NADPH oxidases and reactive oxygen species
por: Mohamed, Raafat, et al.
Publicado: (2019)

Superoxide Dismutase 2 (SOD2) in Vascular Calcification: A Focus on Vascular Smooth Muscle Cells, Calcification Pathogenesis, and Therapeutic Strategies
por: Tsai, You-Tien, et al.
Publicado: (2021)

Vascular Calcification Mechanisms: Updates and Renewed Insight into Signaling Pathways Involved in High Phosphate-Mediated Vascular Smooth Muscle Cell Calcification
por: Abbasian, Nima
Publicado: (2021)

Potential Actions of Baicalein for Preventing Vascular Calcification of Smooth Muscle Cells In Vitro and In Vivo
por: Sulistyowati, Erna, et al.
Publicado: (2022)

Nϵ-Carboxymethyl-Lysine Deteriorates Vascular Calcification in Diabetic Atherosclerosis Induced by Vascular Smooth Muscle Cell-Derived Foam Cells
por: Xu, Sui-Ning, et al.
Publicado: (2020)

Hydrogen sulfide inhibits the calcification and osteoblastic differentiation of vascular smooth muscle cells
por: Zavaczki, Erzsébet, et al.
Publicado: (2011)

Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness
por: Durham, Andrew L, et al.
Publicado: (2018)

Signaling pathways involved in vascular smooth muscle cell calcification during hyperphosphatemia
por: Voelkl, Jakob, et al.
Publicado: (2019)

p53 Regulates Mitochondrial Dynamics in Vascular Smooth Muscle Cell Calcification
por: Phadwal, Kanchan, et al.
Publicado: (2023)

Gαq Is the Specific Mediator of PAR-1 Transactivation of Kinase Receptors in Vascular Smooth Muscle Cells
por: Kamato, Danielle, et al.
Publicado: (2022)

Ablation of the androgen receptor from vascular smooth muscle cells demonstrates a role for testosterone in vascular calcification
por: Zhu, Dongxing, et al.
Publicado: (2016)

Advanced Glycation End-Products Induce Apoptosis of Vascular Smooth Muscle Cells: A Mechanism for Vascular Calcification
por: Koike, Sayo, et al.
Publicado: (2016)

Inflammation and Vascular Calcification Causing Effects of Oxidized HDL are Attenuated by Adiponectin in Human Vascular Smooth Muscle Cells
por: Harun, Noor Hanisa, et al.
Publicado: (2019)

Six Shades of Vascular Smooth Muscle Cells Illuminated by KLF4 (Krüppel-Like Factor 4)
por: Yap, Carmen, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_oeq0qm6cvfln9v2oq0vnoqcl0g