Human HMGA2 protein overexpressed in mice induces precursor T-cell lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is a neoplasia of thymocytes characterized by the rapid accumulation of the precursors of T lymphocytes. HMGA2 (high-mobility group AT-hook 2) gene expression is extremely low in normal adult tissues, but it is overexpressed in many tumors. To identify the...

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Detalles Bibliográficos
Autores principales: Efanov, A, Zanesi, N, Coppola, V, Nuovo, G, Bolon, B, Wernicle-Jameson, D, Lagana, A, Hansjuerg, A, Pichiorri, F, Croce, C M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219444/
https://www.ncbi.nlm.nih.gov/pubmed/25014774
http://dx.doi.org/10.1038/bcj.2014.46

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