Inhibition of Kidney Proximal Tubular Glucose Reabsorption Does Not Prevent against Diabetic Nephropathy in Type 1 Diabetic eNOS Knockout Mice

BACKGROUND AND OBJECTIVE: Sodium glucose cotransporter 2 (SGLT2) is the main luminal glucose transporter in the kidney. SGLT2 inhibition results in glycosuria and improved glycaemic control. Drugs inhibiting this transporter have recently been approved for clinical use and have been suggested to hav...

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Detalles Bibliográficos
Autores principales: Gangadharan Komala, Muralikrishna, Gross, Simon, Mudaliar, Harshini, Huang, Chunling, Pegg, Katherine, Mather, Amanda, Shen, Sylvie, Pollock, Carol A., Panchapakesan, Usha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219667/
https://www.ncbi.nlm.nih.gov/pubmed/25369239
http://dx.doi.org/10.1371/journal.pone.0108994

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