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An Interaction of Renin-Angiotensin and Kallikrein-Kinin Systems Contributes to Vascular Hypertrophy in Angiotensin II-Induced Hypertension: In Vivo and In Vitro Studies

The kallikrein-kinin and renin-angiotensin systems interact at multiple levels. In the present study, we tested the hypothesis that the B1 kinin receptor (B1R) contributes to vascular hypertrophy in angiotensin II (ANG II)–induced hypertension, through a mechanism involving reactive oxygen species (...

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Detalles Bibliográficos
Autores principales: Ceravolo, Graziela S., Montezano, Augusto C., Jordão, Maria T., Akamine, Eliana H., Costa, Tiago J., Takano, Ana P., Fernandes, Denise C., Barreto-Chaves, Maria L., Laurindo, Francisco R., Tostes, Rita C., Fortes, Zuleica B., Chopard, Renato P., Touyz, Rhian M., Carvalho, Maria Helena C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219703/
https://www.ncbi.nlm.nih.gov/pubmed/25369284
http://dx.doi.org/10.1371/journal.pone.0111117