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An Interaction of Renin-Angiotensin and Kallikrein-Kinin Systems Contributes to Vascular Hypertrophy in Angiotensin II-Induced Hypertension: In Vivo and In Vitro Studies
The kallikrein-kinin and renin-angiotensin systems interact at multiple levels. In the present study, we tested the hypothesis that the B1 kinin receptor (B1R) contributes to vascular hypertrophy in angiotensin II (ANG II)–induced hypertension, through a mechanism involving reactive oxygen species (...
Autores principales: | Ceravolo, Graziela S., Montezano, Augusto C., Jordão, Maria T., Akamine, Eliana H., Costa, Tiago J., Takano, Ana P., Fernandes, Denise C., Barreto-Chaves, Maria L., Laurindo, Francisco R., Tostes, Rita C., Fortes, Zuleica B., Chopard, Renato P., Touyz, Rhian M., Carvalho, Maria Helena C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219703/ https://www.ncbi.nlm.nih.gov/pubmed/25369284 http://dx.doi.org/10.1371/journal.pone.0111117 |
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