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Galectin-3 Up-Regulation in Hypoxic and Nutrient Deprived Microenvironments Promotes Cell Survival
Galectin-3 (gal-3) is a β-galactoside binding protein related to many tumoral aspects, e.g. angiogenesis, cell growth and motility and resistance to cell death. Evidence has shown its upregulation upon hypoxia, a common feature in solid tumors such as glioblastoma multiformes (GBM). This tumor prese...
Autores principales: | Ikemori, Rafael Yamashita, Machado, Camila Maria Longo, Furuzawa, Karina Mie, Nonogaki, Suely, Osinaga, Eduardo, Umezawa, Kazuo, de Carvalho, Marcelo Alex, Verinaud, Liana, Chammas, Roger |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219723/ https://www.ncbi.nlm.nih.gov/pubmed/25369297 http://dx.doi.org/10.1371/journal.pone.0111592 |
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