Association of Dowling-Degos disease and multiple seborrheic keratosis in a "Christmas tree pattern"

Dowling-Degos disease is a rare sporadic or autosomal dominant pigmentary entity, in which clusters of papules and reticulate macules slowly develop with predominance in flexural regions. This entity is due to mutations in the keratin 5 gene, and is related with other cutaneous disorders. We report...

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Detalles Bibliográficos
Autores principales: dos Santos, Vitorino Modesto, Pereira, Nayanne Lays dos Santos, Silva, Renata Faria, Silva, Fabio Henrique de Oliveira, Garcia, Cacilda Joyce Ferreira da Silva, Sousa, Maria Aparecida Alves de Figueiredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iran University of Medical Sciences 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219898/
https://www.ncbi.nlm.nih.gov/pubmed/25405133
Descripción
Sumario:Dowling-Degos disease is a rare sporadic or autosomal dominant pigmentary entity, in which clusters of papules and reticulate macules slowly develop with predominance in flexural regions. This entity is due to mutations in the keratin 5 gene, and is related with other cutaneous disorders. We report the sporadic form of Dowling-Degos disease in an elderly man with multiple seborrheic keratosis in a "Christmas tree" pattern. Worthy of note in this case study is the lesions evolved for over than 30 years. The aim is to describe the association of these keratoses with Dowling-Degos disease in a healthy man.

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