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A new pma1 mutation identified in a chronologically long-lived fission yeast mutant
We isolated a chronologically long-lived mutant of Schizosaccharomyces pombe and found a new mutation in pma1(+) that encoded for an essential P-type proton ATPase. An Asp-138 to Asn mutation resulted in reduced Pma1 activity, concomitant with an increase in the chronological lifespan of this fissio...
Autores principales: | Naito, Chikako, Ito, Hirokazu, Oshiro, Tomoko, Ohtsuka, Hokuto, Murakami, Hiroshi, Aiba, Hirofumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219986/ https://www.ncbi.nlm.nih.gov/pubmed/25379379 http://dx.doi.org/10.1016/j.fob.2014.09.006 |
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