Deciphering clonality in aneuploid breast tumors using SNP array and sequencing data

Intra-tumor heterogeneity concerns the existence of genetically different subclones within the same tumor. Single sample quantification of heterogeneity relies on precise determination of chromosomal copy numbers throughout the genome, and an assessment of whether identified mutation variant allele...

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Detalles Bibliográficos
Autores principales: Lönnstedt, Ingrid M, Caramia, Franco, Li, Jason, Fumagalli, Debora, Salgado, Roberto, Rowan, Andrew, Salm, Max, Kanu, Nnennaya, Savas, Peter, Horswell, Stuart, Gade, Stephan, Loibl, Sibylle, Neven, Patrick, Sotiriou, Christos, Swanton, Charles, Loi, Sherene, Speed, Terence P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220069/
https://www.ncbi.nlm.nih.gov/pubmed/25270265
http://dx.doi.org/10.1186/s13059-014-0470-7

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