The Activation of the Sox2 RR2 Pluripotency Transcriptional Reporter in Human Breast Cancer Cell Lines is Dynamic and Labels Cells with Higher Tumorigenic Potential

The striking similarity displayed at the mechanistic level between tumorigenesis and the generation of induced pluripotent stem cells and the fact that genes and pathways relevant for embryonic development are reactivated during tumor progression highlights the link between pluripotency and cancer....

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Detalles Bibliográficos
Autores principales: Iglesias, Juan Manuel, Leis, Olatz, Pérez Ruiz, Estíbaliz, Gumuzio Barrie, Juan, Garcia-Garcia, Francisco, Aduriz, Ariane, Beloqui, Izaskun, Hernandez-Garcia, Susana, Lopez-Mato, Maria Paz, Dopazo, Joaquin, Pandiella, Atanasio, Menendez, Javier A., Martin, Angel Garcia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220105/
https://www.ncbi.nlm.nih.gov/pubmed/25414831
http://dx.doi.org/10.3389/fonc.2014.00308

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