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Combined Immunodeficiency Evolving into Predominant CD4+ Lymphopenia Caused by Somatic Chimerism in JAK3
PURPOSE: Idiopathic CD4 lymphopenia constitutes a heterogeneous group of immunodeficiencies with characteristically low CD4+ T-cell counts with largely unknown genetic etiology. We here sought to determine the underlying molecular cause in an index family with two patients suffering from combined im...
Autores principales: | Ban, Sol A., Salzer, Elisabeth, Eibl, Martha M., Linder, Angela, Geier, Christoph B., Santos-Valente, Elisangela, Garncarz, Wojciech, Lion, Thomas, Ott, Raphael, Seelbach, Christoph, Boztug, Kaan, Wolf, Hermann M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220108/ https://www.ncbi.nlm.nih.gov/pubmed/25205547 http://dx.doi.org/10.1007/s10875-014-0088-2 |
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