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Direct interaction of Plk4 with STIL ensures formation of a single procentriole per parental centriole

Formation of one procentriole next to each pre-existing centriole is essential for centrosome duplication, robust bipolar spindle assembly and maintenance of genome integrity. However, the mechanisms maintaining strict control over centriole copy number are incompletely understood. Here we show that...

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Detalles Bibliográficos
Autores principales: Ohta, Midori, Ashikawa, Tomoko, Nozaki, Yuka, Kozuka-Hata, Hiroko, Goto, Hidemasa, Inagaki, Masaki, Oyama, Masaaki, Kitagawa, Daiju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220463/
https://www.ncbi.nlm.nih.gov/pubmed/25342035
http://dx.doi.org/10.1038/ncomms6267