Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease

The heart is a highly specialized organ with essential function for the organism throughout life. The significance of DNA methylation in shaping the phenotype of the heart remains only partially known. Here we generate and analyse DNA methylomes from highly purified cardiomyocytes of neonatal, adult...

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Detalles Bibliográficos
Autores principales: Gilsbach, Ralf, Preissl, Sebastian, Grüning, Björn A., Schnick, Tilman, Burger, Lukas, Benes, Vladimir, Würch, Andreas, Bönisch, Ulrike, Günther, Stefan, Backofen, Rolf, Fleischmann, Bernd K., Schübeler, Dirk, Hein, Lutz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220495/
https://www.ncbi.nlm.nih.gov/pubmed/25335909
http://dx.doi.org/10.1038/ncomms6288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220495/
https://www.ncbi.nlm.nih.gov/pubmed/25335909
http://dx.doi.org/10.1038/ncomms6288

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