Presynaptic GABAergic inhibition regulated by BDNF contributes to neuropathic pain induction

The gate control theory proposes the importance of both pre- and post-synaptic inhibition in processing pain signal in the spinal cord. However, although postsynaptic disinhibition caused by brain-derived neurotrophic factor (BDNF) has been proved as a crucial mechanism underlying neuropathic pain,...

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Detalles Bibliográficos
Autores principales: Chen, Jeremy Tsung-chieh, Guo, Da, Campanelli, Dario, Frattini, Flavia, Mayer, Florian, Zhou, Luming, Kuner, Rohini, Heppenstall, Paul A., Knipper, Marlies, Hu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220496/
https://www.ncbi.nlm.nih.gov/pubmed/25354791
http://dx.doi.org/10.1038/ncomms6331

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