Antitumor Activity of Monoterpenes Found in Essential Oils

Cancer is a complex genetic disease that is a major public health problem worldwide, accounting for about 7 million deaths each year. Many anticancer drugs currently used clinically have been isolated from plant species or are based on such substances. Accumulating data has revealed anticancer activ...

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Detalles Bibliográficos
Autores principales: Sobral, Marianna Vieira, Xavier, Aline Lira, Lima, Tamires Cardoso, de Sousa, Damião Pergentino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220615/
https://www.ncbi.nlm.nih.gov/pubmed/25401162
http://dx.doi.org/10.1155/2014/953451
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author Sobral, Marianna Vieira
Xavier, Aline Lira
Lima, Tamires Cardoso
de Sousa, Damião Pergentino
author_facet Sobral, Marianna Vieira
Xavier, Aline Lira
Lima, Tamires Cardoso
de Sousa, Damião Pergentino
author_sort Sobral, Marianna Vieira
collection PubMed
description Cancer is a complex genetic disease that is a major public health problem worldwide, accounting for about 7 million deaths each year. Many anticancer drugs currently used clinically have been isolated from plant species or are based on such substances. Accumulating data has revealed anticancer activity in plant-derived monoterpenes. In this review the antitumor activity of 37 monoterpenes found in essential oils is discussed. Chemical structures, experimental models, and mechanisms of action for bioactive substances are presented.
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spelling pubmed-42206152014-11-16 Antitumor Activity of Monoterpenes Found in Essential Oils Sobral, Marianna Vieira Xavier, Aline Lira Lima, Tamires Cardoso de Sousa, Damião Pergentino ScientificWorldJournal Review Article Cancer is a complex genetic disease that is a major public health problem worldwide, accounting for about 7 million deaths each year. Many anticancer drugs currently used clinically have been isolated from plant species or are based on such substances. Accumulating data has revealed anticancer activity in plant-derived monoterpenes. In this review the antitumor activity of 37 monoterpenes found in essential oils is discussed. Chemical structures, experimental models, and mechanisms of action for bioactive substances are presented. Hindawi Publishing Corporation 2014 2014-10-14 /pmc/articles/PMC4220615/ /pubmed/25401162 http://dx.doi.org/10.1155/2014/953451 Text en Copyright © 2014 Marianna Vieira Sobral et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Sobral, Marianna Vieira
Xavier, Aline Lira
Lima, Tamires Cardoso
de Sousa, Damião Pergentino
Antitumor Activity of Monoterpenes Found in Essential Oils
title Antitumor Activity of Monoterpenes Found in Essential Oils
title_full Antitumor Activity of Monoterpenes Found in Essential Oils
title_fullStr Antitumor Activity of Monoterpenes Found in Essential Oils
title_full_unstemmed Antitumor Activity of Monoterpenes Found in Essential Oils
title_short Antitumor Activity of Monoterpenes Found in Essential Oils
title_sort antitumor activity of monoterpenes found in essential oils
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220615/
https://www.ncbi.nlm.nih.gov/pubmed/25401162
http://dx.doi.org/10.1155/2014/953451
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