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Computational Analysis Reveals the Association of Threonine 118 Methionine Mutation in PMP22 Resulting in CMT-1A
The T118M mutation in PMP22 gene is associated with Charcot Marie Tooth, type 1A (CMT1A). CMT1A is a form of Charcot-Marie-Tooth disease, the most common inherited disorder of the peripheral nervous system. Mutations in CMT related disorder are seen to increase the stability of the protein resulting...
Autores principales: | Kumar, Chundi Vinay, Swetha, Rayapadi G., Anbarasu, Anand, Ramaiah, Sudha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220619/ https://www.ncbi.nlm.nih.gov/pubmed/25400662 http://dx.doi.org/10.1155/2014/502618 |
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