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Prognostic and predictive value of Phospho-p44/42 and pAKT in HER2-positive locally advanced breast cancer patients treated with anthracycline-based neoadjuvant chemotherapy

BACKGROUND: To evaluate the predictive and prognostic value of various molecular factors associated with the Ras/MAPK and PI3K/Akt signaling pathways in HER2-positive locally advanced breast cancer patients treated with anthracycline-based neoadjuvant chemotherapy (NAC). METHODS: A total of 113 pati...

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Detalles Bibliográficos
Autores principales: Huang, Liang, Chen, Tianwen, Chen, Canming, Chen, Sheng, Liu, Yin, Wu, Jiong, Shao, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220778/
https://www.ncbi.nlm.nih.gov/pubmed/24289519
http://dx.doi.org/10.1186/1477-7819-11-307