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The chromatin remodelling component SMARCB1/INI1 influences the metastatic behavior of colorectal cancer through a gene signature mapping to chromosome 22

BACKGROUND: INI1 (Integrase interactor 1), also known as SMARCB1, is the most studied subunit of chromatin remodelling complexes. Its role in colorectal tumorigenesis is not known. METHODS: We examined SMARCB1/INI1 protein expression in 134 cases of colorectal cancer (CRC) and 60 matched normal muco...

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Detalles Bibliográficos
Autores principales: Pancione, Massimo, Remo, Andrea, Zanella, Caterina, Sabatino, Lina, Blasi, Arturo Di, Laudanna, Carmelo, Astati, Laura, Rocco, Michele, Bifano, Delfina, Piacentini, Paolo, Pavan, Laura, Purgato, Alberto, Greco, Filippo, Talamini, Alberto, Bonetti, Andrea, Ceccarelli, Michele, Vendraminelli, Roberto, Manfrin, Erminia, Colantuoni, Vittorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220786/
https://www.ncbi.nlm.nih.gov/pubmed/24286138
http://dx.doi.org/10.1186/1479-5876-11-297