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Identification of broadly neutralizing antibody epitopes in the HIV-1 envelope glycoprotein using evolutionary models

BACKGROUND: Identification of the epitopes targeted by antibodies that can neutralize diverse HIV-1 strains can provide important clues for the design of a preventative vaccine. METHODS: We have developed a computational approach that can identify key amino acids within the HIV-1 envelope glycoprote...

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Detalles Bibliográficos
Autores principales:	Lacerda, Miguel, Moore, Penny L, Ngandu, Nobubelo K, Seaman, Michael, Gray, Elin S, Murrell, Ben, Krishnamoorthy, Mohan, Nonyane, Molati, Madiga, Maphuti, Wibmer, Constantinos Kurt, Sheward, Daniel, Bailer, Robert T, Gao, Hongmei, Greene, Kelli M, Karim, Salim S Abdool, Mascola, John R, Korber, Bette TM, Montefiori, David C, Morris, Lynn, Williamson, Carolyn, Seoighe, Cathal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220805/ https://www.ncbi.nlm.nih.gov/pubmed/24295501 http://dx.doi.org/10.1186/1743-422X-10-347

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