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Genome Wide Association Study of Fetal Hemoglobin in Sickle Cell Anemia in Tanzania

BACKGROUND: Fetal hemoglobin (HbF) is an important modulator of sickle cell disease (SCD). HbF has previously been shown to be affected by variants at three loci on chromosomes 2, 6 and 11, but it is likely that additional loci remain to be discovered. METHODS AND FINDINGS: We conducted a genome-wid...

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Detalles Bibliográficos
Autores principales:	Mtatiro, Siana Nkya, Singh, Tarjinder, Rooks, Helen, Mgaya, Josephine, Mariki, Harvest, Soka, Deogratius, Mmbando, Bruno, Msaki, Evarist, Kolder, Iris, Thein, Swee Lay, Menzel, Stephan, Cox, Sharon E., Makani, Julie, Barrett, Jeffrey C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221031/ https://www.ncbi.nlm.nih.gov/pubmed/25372704 http://dx.doi.org/10.1371/journal.pone.0111464

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