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PDE5 Inhibition Improves Object Memory in Standard Housed Rats but Not in Rats Housed in an Enriched Environment: Implications for Memory Models?
Drug effects are usually evaluated in animals housed under maximally standardized conditions. However, it is assumed that an enriched environment (EE) more closely resembles human conditions as compared to maximally standardized laboratory conditions. In the present study, we examined the acute cogn...
Autores principales: | Akkerman, Sven, Prickaerts, Jos, Bruder, Ann K., Wolfs, Kevin H. M., De Vry, Jochen, Vanmierlo, Tim, Blokland, Arjan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221101/ https://www.ncbi.nlm.nih.gov/pubmed/25372140 http://dx.doi.org/10.1371/journal.pone.0111692 |
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