Primary Ovarian Carcinomas and Abdominal Metastasis Contain 4,6-Disulfated Chondroitin Sulfate Rich Regions, Which Provide Adhesive Properties to Tumour Cells

High mortality in ovarian cancer patients is primarily caused through rapid metastasis of the tumour, but the underlying mechanisms are poorly understood. Glycosaminoglycans, are abundantly present in tumours and chondroitin sulfate-E (CSE), a highly 4,6-sulfated glycosaminoglycan, has been indicate...

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Detalles Bibliográficos
Autores principales: Vallen, Myrtille J. E., Schmidt, Samuel, Oosterhof, Arie, Bulten, Johan, Massuger, Leon F. A. G., van Kuppevelt, Toin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221137/
https://www.ncbi.nlm.nih.gov/pubmed/25372710
http://dx.doi.org/10.1371/journal.pone.0111806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221137/
https://www.ncbi.nlm.nih.gov/pubmed/25372710
http://dx.doi.org/10.1371/journal.pone.0111806

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