Targeted Colonic Claudin-2 Expression Renders Resistance to Epithelial Injury, Induces Immune Suppression and Protects from Colitis

Expression of claudin-2, a tight junction protein, is highly upregulated during inflammatory bowel disease (IBD) and, due to its association with epithelial permeability, has been postulated to promote inflammation. Notably, claudin-2 has also been implicated in the regulation of intestinal epitheli...

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Detalles Bibliográficos
Autores principales: Ahmad, Rizwan, Chaturvedi, Rupesh, Olivares-Villagómez, Danyvid, Habib, Tanwir, Asim, Mohammad, Shivesh, Punit, Polk, Brent D., Wilson, Keith T., Washington, Mary K., Van Kaer, Luc, Dhawan, Punita, Singh, Amar B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221190/
https://www.ncbi.nlm.nih.gov/pubmed/24670427
http://dx.doi.org/10.1038/mi.2014.21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221190/
https://www.ncbi.nlm.nih.gov/pubmed/24670427
http://dx.doi.org/10.1038/mi.2014.21

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