Zolpidem Reduces Hippocampal Neuronal Activity in Freely Behaving Mice: A Large Scale Calcium Imaging Study with Miniaturized Fluorescence Microscope

Therapeutic drugs for cognitive and psychiatric disorders are often characterized by their molecular mechanism of action. Here we demonstrate a new approach to elucidate drug action on large-scale neuronal activity by tracking somatic calcium dynamics in hundreds of CA1 hippocampal neurons of pharma...

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Detalles Bibliográficos
Autores principales: Berdyyeva, Tamara, Otte, Stephani, Aluisio, Leah, Ziv, Yaniv, Burns, Laurie D., Dugovic, Christine, Yun, Sujin, Ghosh, Kunal K., Schnitzer, Mark J., Lovenberg, Timothy, Bonaventure, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221229/
https://www.ncbi.nlm.nih.gov/pubmed/25372144
http://dx.doi.org/10.1371/journal.pone.0112068

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