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HemI: A Toolkit for Illustrating Heatmaps

Recent high-throughput techniques have generated a flood of biological data in all aspects. The transformation and visualization of multi-dimensional and numerical gene or protein expression data in a single heatmap can provide a concise but comprehensive presentation of molecular dynamics under dif...

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Detalles Bibliográficos
Autores principales: Deng, Wankun, Wang, Yongbo, Liu, Zexian, Cheng, Han, Xue, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221433/
https://www.ncbi.nlm.nih.gov/pubmed/25372567
http://dx.doi.org/10.1371/journal.pone.0111988
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author Deng, Wankun
Wang, Yongbo
Liu, Zexian
Cheng, Han
Xue, Yu
author_facet Deng, Wankun
Wang, Yongbo
Liu, Zexian
Cheng, Han
Xue, Yu
author_sort Deng, Wankun
collection PubMed
description Recent high-throughput techniques have generated a flood of biological data in all aspects. The transformation and visualization of multi-dimensional and numerical gene or protein expression data in a single heatmap can provide a concise but comprehensive presentation of molecular dynamics under different conditions. In this work, we developed an easy-to-use tool named HemI (Heat map Illustrator), which can visualize either gene or protein expression data in heatmaps. Additionally, the heatmaps can be recolored, rescaled or rotated in a customized manner. In addition, HemI provides multiple clustering strategies for analyzing the data. Publication-quality figures can be exported directly. We propose that HemI can be a useful toolkit for conveniently visualizing and manipulating heatmaps. The stand-alone packages of HemI were implemented in Java and can be accessed at http://hemi.biocuckoo.org/down.php.
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spelling pubmed-42214332014-11-12 HemI: A Toolkit for Illustrating Heatmaps Deng, Wankun Wang, Yongbo Liu, Zexian Cheng, Han Xue, Yu PLoS One Research Article Recent high-throughput techniques have generated a flood of biological data in all aspects. The transformation and visualization of multi-dimensional and numerical gene or protein expression data in a single heatmap can provide a concise but comprehensive presentation of molecular dynamics under different conditions. In this work, we developed an easy-to-use tool named HemI (Heat map Illustrator), which can visualize either gene or protein expression data in heatmaps. Additionally, the heatmaps can be recolored, rescaled or rotated in a customized manner. In addition, HemI provides multiple clustering strategies for analyzing the data. Publication-quality figures can be exported directly. We propose that HemI can be a useful toolkit for conveniently visualizing and manipulating heatmaps. The stand-alone packages of HemI were implemented in Java and can be accessed at http://hemi.biocuckoo.org/down.php. Public Library of Science 2014-11-05 /pmc/articles/PMC4221433/ /pubmed/25372567 http://dx.doi.org/10.1371/journal.pone.0111988 Text en © 2014 Deng et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Deng, Wankun
Wang, Yongbo
Liu, Zexian
Cheng, Han
Xue, Yu
HemI: A Toolkit for Illustrating Heatmaps
title HemI: A Toolkit for Illustrating Heatmaps
title_full HemI: A Toolkit for Illustrating Heatmaps
title_fullStr HemI: A Toolkit for Illustrating Heatmaps
title_full_unstemmed HemI: A Toolkit for Illustrating Heatmaps
title_short HemI: A Toolkit for Illustrating Heatmaps
title_sort hemi: a toolkit for illustrating heatmaps
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221433/
https://www.ncbi.nlm.nih.gov/pubmed/25372567
http://dx.doi.org/10.1371/journal.pone.0111988
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AT xueyu hemiatoolkitforillustratingheatmaps