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Pharmacological Inhibition of the Chemokine CXCL16 Diminishes Liver Macrophage Infiltration and Steatohepatitis in Chronic Hepatic Injury
Non-alcoholic fatty liver disease (NAFLD) is a major cause of morbidity and mortality in developed countries, resulting in steatohepatitis (NASH), fibrosis and eventually cirrhosis. Modulating inflammatory mediators such as chemokines may represent a novel therapeutic strategy for NAFLD. We recently...
Autores principales: | Wehr, Alexander, Baeck, Christer, Ulmer, Florian, Gassler, Nikolaus, Hittatiya, Kanishka, Luedde, Tom, Neumann, Ulf Peter, Trautwein, Christian, Tacke, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221470/ https://www.ncbi.nlm.nih.gov/pubmed/25372401 http://dx.doi.org/10.1371/journal.pone.0112327 |
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