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Molecular Evolution of the Porcine Type I Interferon Family: Subtype-Specific Expression and Antiviral Activity

Type I interferons (IFNs), key antiviral cytokines, evolve to adapt with ever-changing viral threats during vertebrate speciation. Due to novel pathogenic pressure associated with Suidae speciation and domestication, porcine IFNs evolutionarily engender both molecular and functional diversification,...

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Detalles Bibliográficos
Autores principales: Sang, Yongming, Bergkamp, Joseph, Blecha, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221479/
https://www.ncbi.nlm.nih.gov/pubmed/25372927
http://dx.doi.org/10.1371/journal.pone.0112378