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Molecular Evolution of the Porcine Type I Interferon Family: Subtype-Specific Expression and Antiviral Activity
Type I interferons (IFNs), key antiviral cytokines, evolve to adapt with ever-changing viral threats during vertebrate speciation. Due to novel pathogenic pressure associated with Suidae speciation and domestication, porcine IFNs evolutionarily engender both molecular and functional diversification,...
Autores principales: | Sang, Yongming, Bergkamp, Joseph, Blecha, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221479/ https://www.ncbi.nlm.nih.gov/pubmed/25372927 http://dx.doi.org/10.1371/journal.pone.0112378 |
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