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Lentivector Integration Sites in Ependymal Cells From a Model of Metachromatic Leukodystrophy: Non-B DNA as a New Factor Influencing Integration
The blood–brain barrier controls the passage of molecules from the blood into the central nervous system (CNS) and is a major challenge for treatment of neurological diseases. Metachromatic leukodystrophy is a neurodegenerative lysosomal storage disease caused by loss of arylsulfatase A (ARSA) activ...
Autores principales: | McAllister, Robert G, Liu, Jiahui, Woods, Matthew W, Tom, Sean K, Rupar, C Anthony, Barr, Stephen D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221599/ https://www.ncbi.nlm.nih.gov/pubmed/25158091 http://dx.doi.org/10.1038/mtna.2014.39 |
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