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Development of an ELISA assay for the quantification of soluble huntingtin in human blood cells

BACKGROUND: Huntington’s disease (HD) is a monogenic disorder caused by an aberrant expansion of CAG repeats in the huntingtin gene (HTT). Pathogenesis is associated with expression of the mutant (mHTT) protein in the CNS, with its levels most likely related to disease progression and symptom severi...

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Detalles Bibliográficos
Autores principales:	Massai, Luisa, Petricca, Lara, Magnoni, Letizia, Rovetini, Luca, Haider, Salman, Andre, Ralph, Tabrizi, Sarah J, Süssmuth, Sigurd D, Landwehrmeyer, Bernhard G, Caricasole, Andrea, Pollio, Giuseppe, Bernocco, Simonetta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221641/ https://www.ncbi.nlm.nih.gov/pubmed/24274906 http://dx.doi.org/10.1186/1471-2091-14-34

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