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Growth hormone receptor inhibition decreases the growth and metastasis of pancreatic ductal adenocarcinoma
Pancreatic cancer is the only major cancer with very low survival rates (1%). It is the fourth leading cause of cancer-related death. Hyperactivated growth hormone receptor (GHR) levels have been shown to increase the risk of cancer in general and this pathway is a master regulator of key cellular f...
Autores principales: | Subramani, Ramadevi, Lopez-Valdez, Rebecca, Salcido, Alyssa, Boopalan, Thiyagarajan, Arumugam, Arunkumar, Nandy, Sushmita, Lakshmanaswamy, Rajkumar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221692/ https://www.ncbi.nlm.nih.gov/pubmed/25301264 http://dx.doi.org/10.1038/emm.2014.61 |
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