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Dynamic and influential interaction of cancer cells with normal epithelial cells in 3D culture

BACKGROUND: The cancer microenvironment has a strong impact on the growth and dynamics of cancer cells. Conventional 2D culture systems, however, do not reflect in vivo conditions, impeding detailed studies of cancer cell dynamics. This work aims to establish a method to reveal the interaction of ca...

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Detalles Bibliográficos
Autores principales: Ivers, Laura P, Cummings, Brendan, Owolabi, Funke, Welzel, Katarzyna, Klinger, Rut, Saitoh, Sayaka, O’Connor, Darran, Fujita, Yasuyuki, Scholz, Dimitri, Itasaki, Nobue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221723/
https://www.ncbi.nlm.nih.gov/pubmed/25379014
http://dx.doi.org/10.1186/s12935-014-0108-6