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Detection and characterization of zoonotic pathogens of free-ranging non-human primates from Zambia
BACKGROUND: Wildlife may harbor infectious pathogens that are of zoonotic concern acting as a reservoir of diseases transmissible to humans and domestic animals. This is due to human-wildlife conflicts that have become more frequent and severe over recent decades, competition for the available natur...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221724/ https://www.ncbi.nlm.nih.gov/pubmed/25358853 http://dx.doi.org/10.1186/s13071-014-0490-x |
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author | Nakayima, Jesca Hayashida, Kyoko Nakao, Ryo Ishii, Akihiro Ogawa, Hirohito Nakamura, Ichiro Moonga, Ladslav Hang’ombe, Bernard M Mweene, Aaron S Thomas, Yuka Orba, Yasuko Sawa, Hirofumi Sugimoto, Chihiro |
author_facet | Nakayima, Jesca Hayashida, Kyoko Nakao, Ryo Ishii, Akihiro Ogawa, Hirohito Nakamura, Ichiro Moonga, Ladslav Hang’ombe, Bernard M Mweene, Aaron S Thomas, Yuka Orba, Yasuko Sawa, Hirofumi Sugimoto, Chihiro |
author_sort | Nakayima, Jesca |
collection | PubMed |
description | BACKGROUND: Wildlife may harbor infectious pathogens that are of zoonotic concern acting as a reservoir of diseases transmissible to humans and domestic animals. This is due to human-wildlife conflicts that have become more frequent and severe over recent decades, competition for the available natural habitats and resources leading to increased human encroachment on previously wild and uninhabited areas. METHODS: A total of 88 spleen DNA samples from baboons and vervet monkeys from Zambia were tested for zoonotic pathogens using genus or species-specific PCR. The amplified products were then subjected to sequencing analysis. RESULTS: We detected three different pathogenic agents, including Anaplasma phagocytophilum in 12 samples (13.6%), Rickettsia spp. in 35 samples (39.8%) and Babesia spp. in 2 samples (2.3%). CONCLUSION: The continuously increasing contacts between humans and primate populations raise concerns about transmission of pathogens between these groups. Therefore, increased medical and public awareness and public health surveillance support will be required to detect and control infections caused by these agents at the interface between humans and wildlife. |
format | Online Article Text |
id | pubmed-4221724 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-42217242014-11-07 Detection and characterization of zoonotic pathogens of free-ranging non-human primates from Zambia Nakayima, Jesca Hayashida, Kyoko Nakao, Ryo Ishii, Akihiro Ogawa, Hirohito Nakamura, Ichiro Moonga, Ladslav Hang’ombe, Bernard M Mweene, Aaron S Thomas, Yuka Orba, Yasuko Sawa, Hirofumi Sugimoto, Chihiro Parasit Vectors Research BACKGROUND: Wildlife may harbor infectious pathogens that are of zoonotic concern acting as a reservoir of diseases transmissible to humans and domestic animals. This is due to human-wildlife conflicts that have become more frequent and severe over recent decades, competition for the available natural habitats and resources leading to increased human encroachment on previously wild and uninhabited areas. METHODS: A total of 88 spleen DNA samples from baboons and vervet monkeys from Zambia were tested for zoonotic pathogens using genus or species-specific PCR. The amplified products were then subjected to sequencing analysis. RESULTS: We detected three different pathogenic agents, including Anaplasma phagocytophilum in 12 samples (13.6%), Rickettsia spp. in 35 samples (39.8%) and Babesia spp. in 2 samples (2.3%). CONCLUSION: The continuously increasing contacts between humans and primate populations raise concerns about transmission of pathogens between these groups. Therefore, increased medical and public awareness and public health surveillance support will be required to detect and control infections caused by these agents at the interface between humans and wildlife. BioMed Central 2014-10-29 /pmc/articles/PMC4221724/ /pubmed/25358853 http://dx.doi.org/10.1186/s13071-014-0490-x Text en © Nakayima et al.; licensee BioMed Central Ltd. 2014 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Nakayima, Jesca Hayashida, Kyoko Nakao, Ryo Ishii, Akihiro Ogawa, Hirohito Nakamura, Ichiro Moonga, Ladslav Hang’ombe, Bernard M Mweene, Aaron S Thomas, Yuka Orba, Yasuko Sawa, Hirofumi Sugimoto, Chihiro Detection and characterization of zoonotic pathogens of free-ranging non-human primates from Zambia |
title | Detection and characterization of zoonotic pathogens of free-ranging non-human primates from Zambia |
title_full | Detection and characterization of zoonotic pathogens of free-ranging non-human primates from Zambia |
title_fullStr | Detection and characterization of zoonotic pathogens of free-ranging non-human primates from Zambia |
title_full_unstemmed | Detection and characterization of zoonotic pathogens of free-ranging non-human primates from Zambia |
title_short | Detection and characterization of zoonotic pathogens of free-ranging non-human primates from Zambia |
title_sort | detection and characterization of zoonotic pathogens of free-ranging non-human primates from zambia |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221724/ https://www.ncbi.nlm.nih.gov/pubmed/25358853 http://dx.doi.org/10.1186/s13071-014-0490-x |
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