A review on the use of cell therapy in the treatment of tendon disease and injuries

Tendon disease and injuries carry significant morbidity worldwide in both athletic and non-athletic populations. It is estimated that tendon injuries account for 30%−50% of all musculoskeletal injuries globally. Current treatments have been inadequate in providing an accelerated process of repair re...

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Autores principales: Ho, Jasmine OY, Sawadkar, Prasad, Mudera, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221986/
https://www.ncbi.nlm.nih.gov/pubmed/25383170
http://dx.doi.org/10.1177/2041731414549678
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author Ho, Jasmine OY
Sawadkar, Prasad
Mudera, Vivek
author_facet Ho, Jasmine OY
Sawadkar, Prasad
Mudera, Vivek
author_sort Ho, Jasmine OY
collection PubMed
description Tendon disease and injuries carry significant morbidity worldwide in both athletic and non-athletic populations. It is estimated that tendon injuries account for 30%−50% of all musculoskeletal injuries globally. Current treatments have been inadequate in providing an accelerated process of repair resulting in high relapse rates. Modern concepts in tissue engineering and regenerative medicine have led to increasing interest in the application of cell therapy for the treatment of tendon disease. This review will explore the use of cell therapy, by bringing together up-to-date evidence from in vivo human and animal studies, and discuss the issues surrounding the safety and efficacy of its use in the treatment of tendon disease.
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spelling pubmed-42219862014-11-07 A review on the use of cell therapy in the treatment of tendon disease and injuries Ho, Jasmine OY Sawadkar, Prasad Mudera, Vivek J Tissue Eng Review Tendon disease and injuries carry significant morbidity worldwide in both athletic and non-athletic populations. It is estimated that tendon injuries account for 30%−50% of all musculoskeletal injuries globally. Current treatments have been inadequate in providing an accelerated process of repair resulting in high relapse rates. Modern concepts in tissue engineering and regenerative medicine have led to increasing interest in the application of cell therapy for the treatment of tendon disease. This review will explore the use of cell therapy, by bringing together up-to-date evidence from in vivo human and animal studies, and discuss the issues surrounding the safety and efficacy of its use in the treatment of tendon disease. SAGE Publications 2014-09-18 /pmc/articles/PMC4221986/ /pubmed/25383170 http://dx.doi.org/10.1177/2041731414549678 Text en © The Author(s) 2014 http://creativecommons.org/licenses/by-nc/3.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (http://www.uk.sagepub.com/aboutus/openaccess.htm).
spellingShingle Review
Ho, Jasmine OY
Sawadkar, Prasad
Mudera, Vivek
A review on the use of cell therapy in the treatment of tendon disease and injuries
title A review on the use of cell therapy in the treatment of tendon disease and injuries
title_full A review on the use of cell therapy in the treatment of tendon disease and injuries
title_fullStr A review on the use of cell therapy in the treatment of tendon disease and injuries
title_full_unstemmed A review on the use of cell therapy in the treatment of tendon disease and injuries
title_short A review on the use of cell therapy in the treatment of tendon disease and injuries
title_sort review on the use of cell therapy in the treatment of tendon disease and injuries
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221986/
https://www.ncbi.nlm.nih.gov/pubmed/25383170
http://dx.doi.org/10.1177/2041731414549678
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