α-santalol inhibits the angiogenesis and growth of human prostate tumor growth by targeting vascular endothelial growth factor receptor 2-mediated AKT/mTOR/P70S6K signaling pathway

BACKGROUND: VEGF receptor 2 (VEGFR2) inhibitors, as efficient antiangiogenesis agents, have been applied in the cancer treatment. However, recently, most of these anticancer drugs have some adverse effects. Discovery of novel VEGFR2 inhibitors as anticancer drug candidates is still needed. METHODS:...

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Detalles Bibliográficos
Autores principales: Saraswati, Sarita, Kumar, Shakti, Alhaider, Abdulqader A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221991/
https://www.ncbi.nlm.nih.gov/pubmed/24261856
http://dx.doi.org/10.1186/1476-4598-12-147

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