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Giant Fibroadenoma Growing Rapidly During Pregnancy

INTRODUCTION: Giant fibroadenoma is a rare disease with unknown etiology. During pregnancy, fibroadenomas increase in size and may show lactational histologic changes. High concentrations of estrogen, progesterone, and prolactin promote the ductal growth and formation of tubuloalveolar structures. T...

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Autores principales: Karagulle, Erdal, Turk, Emin, Erinanc, Ozgur Hilal, Moray, Gokhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222024/
https://www.ncbi.nlm.nih.gov/pubmed/25389498
http://dx.doi.org/10.5812/ircmj.9531
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author Karagulle, Erdal
Turk, Emin
Erinanc, Ozgur Hilal
Moray, Gokhan
author_facet Karagulle, Erdal
Turk, Emin
Erinanc, Ozgur Hilal
Moray, Gokhan
author_sort Karagulle, Erdal
collection PubMed
description INTRODUCTION: Giant fibroadenoma is a rare disease with unknown etiology. During pregnancy, fibroadenomas increase in size and may show lactational histologic changes. High concentrations of estrogen, progesterone, and prolactin promote the ductal growth and formation of tubuloalveolar structures. This may be a reason for the significant enlargement in this period. CASE PRESENTATION: We presented a case of giant fibroadenoma, first detected at the onset of pregnancy, which grew rapidly and was excised surgically two months after the birth. There was no marked deformity in the breast nor a need to reconstruct it, despite the giant mass was excised and the mother was lactating. DISCUSSION: We presented a rare case of giant fibroadenoma in a lactating woman. A progressively growing mass in breast can lead to structural damages. The current management approach for giant fibroadenomas is still surgical excision.
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spelling pubmed-42220242014-11-11 Giant Fibroadenoma Growing Rapidly During Pregnancy Karagulle, Erdal Turk, Emin Erinanc, Ozgur Hilal Moray, Gokhan Iran Red Crescent Med J Case Report INTRODUCTION: Giant fibroadenoma is a rare disease with unknown etiology. During pregnancy, fibroadenomas increase in size and may show lactational histologic changes. High concentrations of estrogen, progesterone, and prolactin promote the ductal growth and formation of tubuloalveolar structures. This may be a reason for the significant enlargement in this period. CASE PRESENTATION: We presented a case of giant fibroadenoma, first detected at the onset of pregnancy, which grew rapidly and was excised surgically two months after the birth. There was no marked deformity in the breast nor a need to reconstruct it, despite the giant mass was excised and the mother was lactating. DISCUSSION: We presented a rare case of giant fibroadenoma in a lactating woman. A progressively growing mass in breast can lead to structural damages. The current management approach for giant fibroadenomas is still surgical excision. Kowsar 2014-08-05 2014-08 /pmc/articles/PMC4222024/ /pubmed/25389498 http://dx.doi.org/10.5812/ircmj.9531 Text en Copyright © 2014, Iranian Red Crescent Medical Journal; Published by Kowsar Corp. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Karagulle, Erdal
Turk, Emin
Erinanc, Ozgur Hilal
Moray, Gokhan
Giant Fibroadenoma Growing Rapidly During Pregnancy
title Giant Fibroadenoma Growing Rapidly During Pregnancy
title_full Giant Fibroadenoma Growing Rapidly During Pregnancy
title_fullStr Giant Fibroadenoma Growing Rapidly During Pregnancy
title_full_unstemmed Giant Fibroadenoma Growing Rapidly During Pregnancy
title_short Giant Fibroadenoma Growing Rapidly During Pregnancy
title_sort giant fibroadenoma growing rapidly during pregnancy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222024/
https://www.ncbi.nlm.nih.gov/pubmed/25389498
http://dx.doi.org/10.5812/ircmj.9531
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