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Deep Sequencing Identifies Noncanonical Editing of Ebola and Marburg Virus RNAs in Infected Cells

Deep sequencing of RNAs produced by Zaire ebolavirus (EBOV) or the Angola strain of Marburgvirus (MARV-Ang) identified novel viral and cellular mechanisms that diversify the coding and noncoding sequences of viral mRNAs and genomic RNAs. We identified previously undescribed sites within the EBOV and...

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Detalles Bibliográficos
Autores principales: Shabman, Reed S., Jabado, Omar J., Mire, Chad E., Stockwell, Timothy B., Edwards, Megan, Mahajan, Milind, Geisbert, Thomas W., Basler, Christopher F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222107/
https://www.ncbi.nlm.nih.gov/pubmed/25370495
http://dx.doi.org/10.1128/mBio.02011-14