The power-proportion method for intracranial volume correction in volumetric imaging analysis

In volumetric brain imaging analysis, volumes of brain structures are typically assumed to be proportional or linearly related to intracranial volume (ICV). However, evidence abounds that many brain structures have power law relationships with ICV. To take this relationship into account in volumetri...

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Detalles Bibliográficos
Autores principales: Liu, Dawei, Johnson, Hans J., Long, Jeffrey D., Magnotta, Vincent A., Paulsen, Jane S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222222/
https://www.ncbi.nlm.nih.gov/pubmed/25414635
http://dx.doi.org/10.3389/fnins.2014.00356
Descripción
Sumario:In volumetric brain imaging analysis, volumes of brain structures are typically assumed to be proportional or linearly related to intracranial volume (ICV). However, evidence abounds that many brain structures have power law relationships with ICV. To take this relationship into account in volumetric imaging analysis, we propose a power law based method—the power-proportion method—for ICV correction. The performance of the new method is demonstrated using data from the PREDICT-HD study.

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