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Lung mesenchymal expression of Sox9 plays a critical role in tracheal development

BACKGROUND: Embryonic lung development is instructed by crosstalk between mesenchyme and epithelia, which results in activation of transcriptional factors, such as Sox9, in a temporospatial manner. Sox9 is expressed in both distal lung epithelium and proximal lung mesenchyme. Here, we investigated t...

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Detalles Bibliográficos
Autores principales: Turcatel, Gianluca, Rubin, Nicole, Menke, Douglas B, Martin, Gary, Shi, Wei, Warburton, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222279/
https://www.ncbi.nlm.nih.gov/pubmed/24274029
http://dx.doi.org/10.1186/1741-7007-11-117