A versatile δ-aminolevulinic acid (ΑLA)-cyclodextrin bimodal conjugate-prodrug for PDT applications with the help of intracellular chemistry

Grafting of δ-aminolevulinic acid (1) moieties on the narrow periphery of a β-cyclodextrin (β-CD) derivative through hydrolysable bonds was implemented, in order to generate a water-soluble, molecular/drug carrier with the capacity to undergo intracellular transformation into protoporphyrin IX (PpIX...

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Detalles Bibliográficos
Autores principales: Aggelidou, Chrysie, Theodossiou, Theodossis A, Gonçalves, Antonio Ricardo, Lampropoulou, Mariza, Yannakopoulou, Konstantina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222291/
https://www.ncbi.nlm.nih.gov/pubmed/25383111
http://dx.doi.org/10.3762/bjoc.10.251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222291/
https://www.ncbi.nlm.nih.gov/pubmed/25383111
http://dx.doi.org/10.3762/bjoc.10.251

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