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A versatile δ-aminolevulinic acid (ΑLA)-cyclodextrin bimodal conjugate-prodrug for PDT applications with the help of intracellular chemistry
Grafting of δ-aminolevulinic acid (1) moieties on the narrow periphery of a β-cyclodextrin (β-CD) derivative through hydrolysable bonds was implemented, in order to generate a water-soluble, molecular/drug carrier with the capacity to undergo intracellular transformation into protoporphyrin IX (PpIX...
Autores principales: | Aggelidou, Chrysie, Theodossiou, Theodossis A, Gonçalves, Antonio Ricardo, Lampropoulou, Mariza, Yannakopoulou, Konstantina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222291/ https://www.ncbi.nlm.nih.gov/pubmed/25383111 http://dx.doi.org/10.3762/bjoc.10.251 |
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