Cargando…

Formal total syntheses of classic natural product target molecules via palladium-catalyzed enantioselective alkylation

Pd-catalyzed enantioselective alkylation in conjunction with further synthetic elaboration enables the formal total syntheses of a number of “classic” natural product target molecules. This publication highlights recent methods for setting quaternary and tetrasubstituted tertiary carbon stereocenter...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Yiyang, Liniger, Marc, McFadden, Ryan M, Roizen, Jenny L, Malette, Jacquie, Reeves, Corey M, Behenna, Douglas C, Seto, Masaki, Kim, Jimin, Mohr, Justin T, Virgil, Scott C, Stoltz, Brian M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2014
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222294/ https://www.ncbi.nlm.nih.gov/pubmed/25383121 http://dx.doi.org/10.3762/bjoc.10.261

Ejemplares similares

Enantioselective Construction of Quaternary N-Heterocycles by Palladium-Catalyzed Decarboxylative Allylic Alkylation of Lactams
por: Behenna, Douglas C., et al.
Publicado: (2011)

Palladium-Catalyzed Enantioselective Decarboxylative Allylic Alkylation of Cyclopentanones
por: Craig, Robert A., et al.
Publicado: (2015)

Development of (Trimethylsilyl)ethyl Ester Protected Enolates and Applications in Palladium-Catalyzed Enantioselective Allylic Alkylation: Intermolecular Cross-Coupling of Functionalized Electrophiles
por: Reeves, Corey M., et al.
Publicado: (2014)

Enantioselective Synthesis of α-Quaternary Mannich Adducts by Palladium-Catalyzed Allylic Alkylation: Total Synthesis of (+)-Sibirinine
por: Numajiri, Yoshitaka, et al.
Publicado: (2015)

Palladium-catalyzed enantioselective decarboxylative allylic alkylation of fully substituted N-acyl indole-derived enol carbonates
por: Alexy, Eric J., et al.
Publicado: (2019)

Tandem Dearomatization/Enantioselective Allylic Alkylation of Pyridines
por: Greßies, Steffen, et al.
Publicado: (2023)

Nickel-catalyzed enantioselective allylic alkylation of lactones and lactams with unactivated allylic alcohols
por: Ngamnithiporn, Aurapat, et al.
Publicado: (2018)

A palladium-catalysed enolate alkylation cascade for the formation of adjacent quaternary and tertiary stereocentres
por: Streuff, Jan, et al.
Publicado: (2010)

Enantioselective synthesis of highly oxygenated acyclic quaternary center-containing building blocks via palladium-catalyzed decarboxylative allylic alkylation of cyclic siloxyketones
por: Ngamnithiporn, Aurapat, et al.
Publicado: (2020)

A Catalytic, Enantioselective Formal Synthesis of (+)-Dichroanone and (+)-Taiwaniaquinone H
por: Shockley, Samantha E., et al.
Publicado: (2014)

Correction: Enantioselective, convergent synthesis of the ineleganolide core by a tandem annulation cascade
por: Craig, Robert A., et al.
Publicado: (2019)

Enantioselective, convergent synthesis of the ineleganolide core by a tandem annulation cascade
por: Craig, II, Robert A., et al.
Publicado: (2017)

Origins of Enhanced Enantioselectivity in the Pd-Catalyzed Decarboxylative Allylic Alkylation of N-Benzoyl Lactams ()
por: Cusumano, Alexander Q., et al.
Publicado: (2023)

Enantioselective synthesis of gem-disubstituted N-Boc diazaheterocycles via decarboxylative asymmetric allylic alkylation
por: Sun, Alexander W., et al.
Publicado: (2018)

Palladium-Catalyzed, Enantioselective Formal Cycloaddition between Benzyltriflamides and Allenes: Straightforward Access to Enantioenriched Isoquinolines
por: Vidal, Xandro, et al.
Publicado: (2019)

Cooperative Palladium/Isothiourea Catalyzed Enantioselective Formal (3+2) Cycloaddition of Vinylcyclopropanes and α,β‐Unsaturated Esters
por: Bitai, Jacqueline, et al.
Publicado: (2022)

Palladium-Catalyzed, Enantioselective Heine Reaction
por: Punk, Molly, et al.
Publicado: (2016)

Palladium-catalyzed asymmetric allylic alkylation (AAA) with alkyl sulfones as nucleophiles
por: Trost, Barry M., et al.
Publicado: (2021)

Probing Regio- and Enantioselectivity in the Formal [2 + 2] Cycloaddition of C(1)-Alkyl Ammonium Enolates with β- and α,β-Substituted Trifluoromethylenones
por: Wang, Yihong, et al.
Publicado: (2023)

Catalytic enantioselective synthesis of tetrasubstituted chromanones via palladium-catalyzed asymmetric conjugate arylation using chiral pyridine-dihydroisoquinoline ligands
por: Baek, Doohyun, et al.
Publicado: (2020)

Palladium-catalyzed enantioselective alkenylation of alkenylbenzene derivatives
por: Chen, Zhi-Min, et al.
Publicado: (2019)

Palladium-catalyzed enantioselective rearrangement of dienyl cyclopropanes
por: Xu, Qi, et al.
Publicado: (2023)

Efficient syntheses of (–)-crinine and (–)-aspidospermidine, and the formal synthesis of (–)-minfiensine by enantioselective intramolecular dearomative cyclization
por: Du, Kang, et al.
Publicado: (2017)

Hydroxy-directed iridium-catalyzed enantioselective formal β-C(sp(2))–H allylic alkylation of α,β-unsaturated carbonyls
por: Mitra, Sankash, et al.
Publicado: (2022)

Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to α,β-Unsaturated Lactams: Enantioselective Construction of All-Carbon Quaternary Stereocenters in Saturated Nitrogen-Containing Heterocycles
por: Zhang, Tianyi, et al.
Publicado: (2023)

Palladium-Catalyzed Enantioselective 1,1-Fluoroarylation of Aminoalkenes
por: He, Ying, et al.
Publicado: (2015)

Synergistic formal ring contraction for the enantioselective synthesis of spiropyrazolones
por: Meazza, Marta, et al.
Publicado: (2018)

Catalytic Enantioselective Cyclization/Cross-Coupling with Alkyl Electrophiles
por: Cong, Huan, et al.
Publicado: (2014)

Catalytic photochemical enantioselective α-alkylation with pyridinium salts
por: Yetra, Santhivardhana Reddy, et al.
Publicado: (2022)

Enantioselective N-heterocyclic carbene-catalyzed nucleophilic dearomatization of alkyl pyridiniums
por: Flanigan, Darrin M., et al.
Publicado: (2017)

Enantioselective palladium-catalyzed diboration of 1,1-disubstituted allenes
por: Liu, Jiawang, et al.
Publicado: (2017)

Electrooxidative palladium- and enantioselective rhodium-catalyzed [3 + 2] spiroannulations
por: Wei, Wen, et al.
Publicado: (2022)

Iridium-catalyzed enantioselective direct vinylogous allylic alkylation of coumarins
por: Sarkar, Rahul, et al.
Publicado: (2018)

Tandem Friedel‐Crafts‐Alkylation‐Enantioselective‐Protonation by Artificial Enzyme Iminium Catalysis
por: Leveson‐Gower, Reuben B., et al.
Publicado: (2022)

Enantioselective Csp3-Csp3 formation by nickel-catalyzed enantioconvergent cross-electrophile alkyl-alkyl coupling of unactivated alkyl halides
por: Zhao, Wen-Tao, et al.
Publicado: (2023)

Stretchable chiral pockets for palladium-catalyzed highly chemo- and enantioselective allenylation
por: Zhang, Yuchen, et al.
Publicado: (2021)

Enantioselective difunctionalization of alkenes by a palladium-catalyzed Heck/borylation sequence
por: Wu, Yuanqi, et al.
Publicado: (2022)

Studying the reactivity of alkyl substituted BODIPYs: first enantioselective addition of BODIPY to MBH carbonates
por: Meazza, Marta, et al.
Publicado: (2021)

Nitro-enabled catalytic enantioselective formal umpolung alkenylation of β-ketoesters
por: Choudhury, Abhijnan Ray, et al.
Publicado: (2017)

Access to P-chiral phosphine oxides by enantioselective allylic alkylation of bisphenols
por: Yang, Guo-Hui, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_dj1p5r0ekaeqmjkpbsg1mbpmcn