Changes in Methylation Patterns of Kiss1 and Kiss1r Gene Promoters Across Puberty

The initiation of mammalian puberty is underpinned by an increase in Kisspeptin (Kiss1) signaling via its receptor (Kiss1r/GPR54) on gonadotropin-releasing hormone (GnRH) neurons. Animals and humans with loss-of-function mutations in Kiss1 or Kiss1r fail to go through puberty. The timing of puberty...

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Detalles Bibliográficos
Autores principales: Wyatt, Amanda K, Zavodna, Monika, Viljoen, Jean L, Stanton, Jo-Ann L, Gemmell, Neil J, Jasoni, Christine L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222338/
https://www.ncbi.nlm.nih.gov/pubmed/25512707
http://dx.doi.org/10.4137/GEG.S12897

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